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However, unlessfrom this group that are used in PIC include fen- effective plasma concentrations of the drug havetanyl, alfentanil and remifentanil. This binding pre-cedes most manifestations of toxicity, and the extent ofbinding often correlates well with toxicity

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Bowman's capsule (BC) is shown on the left; it is continuous at thedashedline (marked by arrowheads) with the tubule cells ofthe proximal tubule {PTC).

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